Since orgasms cause a release of endorphins into one's cerebral-spinal fluid and endorphins are also somewhat responsible for the emotion of happiness, etc., is it possible that excessive masturbation and/or intercourse would lead to a depleted level of endorphins in the system that could in turn cause one's affect to become somewhat "flat"? Could a sustained low level of endorphins in the system induce depression and/or mood disorder?

1) In my shopping and looking for condoms, I NEVER come across a formal size chart. I have been told that I was "endowed" and that I need to look toward larger sized models, but all I ever see is "snug fit," "large," and "extra large," etc. How big is big? It would be most helpful if I knew what I was buying before I actually bought it. Do you know of the sizes of some popular condoms, or of a size chart resource?

2) I have just started sleeping with my girlfriend and I was a virgin previously. Unfortunately, a slight problem has interfered... I tried to use a condom the first time (a free one from Health Services) and it was too small on me. I only rolled up about 3/4 of the way and was *very* uncomfortable. Is there any specific brand that I could use that would be more comfortable?

I was wondering about the depth of the vagina. I've read statistics that say that the average vagina is only 3 to 4 inches deep. This seems way too small to me, since the average penis is considerably longer than that. Wouldn't that mean that most penises would crash into the cervix repeatedly during intercourse? Since this obviously doesn't happen, my question is this: does the vagina actually elongate during intercourse to accommodate the entire length of the average penis?

Dear Alice, 

I take Valtrex daily to protect me from cold sores I get on my face. I haven’t had one since I started taking it a few years ago. My partner gets cold sores on his mouth and has recently performed oral sex on me while having a cold sore. Will the daily Valtrex protect me from developing genital herpes? How will this affect me in the future?

I would like to know what you've heard about pierced clitori. I've been told that the clitoris is one of the fastest parts of the body to heal after it is pierced, and that piercing it heightens sexual pleasure. Is there any truth to these rumors?

Hi! I have a question about orgasms. I'm a female who has masturbated since her early teens and wonder if I've "overdone" it somewhat. I did it so frequently (sometimes every other day or so; sometimes I waited longer) that now that I'm in my early 20s, I find it harder to reach orgasm, and harder to have multiple orgasms (it used to come so easily to me). Have I "lost" that momentum? Can I regain it if, say, I stopped masturbating for several weeks or months?

Also, my partner stimulates me manually or with his tongue, and I haven't been able to "come" yet... is it because I've masturbated too much? Do women take longer to come? I think he gets bored doing it...

I have recently been advised that my on-going migraines might be caused and/or increased by the use of contraceptives containing estrogen. To that end, I have been recommended to switch to a progesterone-only form of birth control. Which, in turn, basically means I get to choose between Implanon and Mirena (I really can't stand needles, so Depo is out for me!). I am only 23 years old, and have not yet started a family. I do want to have children someday, and am very enticed by the idea of Mirena lasting to the point when I might want to begin trying to get pregnant. However, all of the advertisements for Mirena state that ideal candidates have already had children.

Is Mirena still safe for use in women who have not yet given birth? If so are there any additional side effects to consider in this instance?

1) Recently, during intercourse, my condom broke. Now, of course, I am very worried about it happening again. I am constantly checking the condom during sex and find that the condom is extremely tight against the tip of my penis whenever I check. I am afraid it will get tight again and break. I'm not sure what to do or where to go. Is the condom supposed to be very tight at the tip or not? Any help would be great.

2) Here's my query. I recently started having sex, and we are committed to using condoms. What is the "right" way to use a condom? I know how to put them on and take them off. But I'm petrified about having it break or come off. Also, someone told me that I should pull out immediately after I ejaculate. Is this true? This has happened before, but I have "stayed in" because I wanted my partner to have an orgasm. Is it really important to withdraw immediately after ejaculation?

I am not sure who the father of my son is. Is it possible to tell the father of the baby simply by knowing blood types and Rh factors of myself and the potential fathers?

1) I have recently discovered that I have what appear to be crabs in my pubic hair. They are itchy and annoying and appear to be laying eggs. How do I get rid of them?

2) I think I have pubic lice, a.k.a. "crabs." Do I need to see a doctor about this problem, or is there over-the-counter medication of some kind I can use to expel the little buggers from their new home? Also, I'm curious as to how I got them since I haven't had sex for several months and this is a recent development. Can one contract this problem from sharing clothing, towels, or bedclothes?

What are the risks of HIV infection for the passive partner of oral sex?

My wife and I had our first child last July. Until about 3 months ago, she was unable to reach orgasm at all. Of late, she has very small one's, but they don't seem to be getting much better. Prior to having the baby, she had strong, very quick (3-5 minutes) orgasms 90% of the time. I know the stress of being at work rather than home with the baby could play a part in this. Is this common and is there a way to mitigate the problem? 

If one has a long-term partner and neither AIDS nor any other STD is a concern, is there any medical reason not to perform cunnilingus on a menstruating woman? My significant other is particularly horny during her period and would love cunnilingus at this time. I am willing but curious.