Is there a connection between cortisol, depression, and weight loss?

I recently went to my doctor because I've been unable to lose weight. I've been on a successful diet, accompanied with a reasonable exercise plan, but I've seen no real results. A series of tests were run — I've got optimum blood pressure, low cholesterol, and I am not diabetic. But, when my cortisol levels were checked — they were very high. The doctor suspected there was a possibility that I might have Cushings' Syndrome — but another test was run and that came up negative.

I was doing research on the internet, and I found that there was a link between excessive cortisol and depression. I was diagnosed with clinical depression when I was 12 (I am now 21). And I am currently untreated. What is the link between cortisol levels and depression? Are excessive cortisol levels a physical manifestation of depression? Or does an excess of cortisol for some other reason cause depression? Does an excessive amount of cortisol cause weight gain, or in my case prohibit weight loss? And if there is a connection — will treatment for my clinical depression (in the form of prescription pills) help me?

I've been unable to find answers anywhere, or at least a good source to tell me to stop worrying — any help would be appreciated.


Why do I still feel sick after drinking weeks ago?

I am a 23 year old female who enjoys a few glasses of wine but, in my opinion, doesn't drink more than the average college student. A few weeks ago, I had quite a bit to drink and haven't felt the same since. I am dizzy, forgetful, confused and my liver is very tender to the touch. I have continued to have a few glasses of wine a couple nights out of the week and it seems to be the only thing that gets me back to feeling "normal." Is this a normal way to feel or should I be concerned?


Is my vegetarian diet making me feel tired?

I am a vegetarian and frequently feel like it takes a long time to "wake up" in the morning and some days I feel like I never quite get there. I can't help but think this may be diet related. I went to a doctor for a test for anemia which was negative and I always try to get a good nights' sleep (six to eight hours). In the past I have tried to gain weight and failed miserably. I remain a little underweight but get a good deal of exercise each day. Any ideas?


Are there health concerns associated with consuming Sucralose (Splenda)?

1) What are your thoughts regarding the use of Splenda as a sugar substitute? I have heard that the body is not able to metabolize this and that it is excreted through the urine. Do you have any current research on Splenda and the side effects? I realize it is a relatively new product. Thank you!

2) I searched the archives and found no information on Splenda or sucralose. Lately, it seems like Splenda is gaining popularity in the crowded sugar-substitute category. It seems too good to be true — measures cup for cup like sugar, you can bake with it and mix it into drinks, and it is made from sugar so it really tastes like sugar. My two questions are... is this a safe product, or are there some disadvantages with the product? And secondly, if it is very safe and versatile, why aren't more companies using it now?