I think it would be a good idea for me to stop smoking marijuana and cut down on my drinking, at least during the school year. The problem is, I have been doing it for so long it is almost as though I have forgotten how to have fun without it. Contributing to this problem is the fact that many of my friends smoke or drink to have fun. Many of my other friends just do not seem to have fun at all; they stay in Friday and Saturday nights to do work. I've found it difficult to quit, I think because I'm just not sure of what's out there to do that's fun without being stoned or drunk. Can you recommend anything that's fun whether you're intoxicated or sober, so that I don't have to stop hanging out with certain friends if I want to relax and have fun? I want to finally enjoy life without relying on an altered state of consciousness. What's there to do when you're sick of renting movies? Also, any tips for resisting the urge to take people up on their offer to toke up? (I'm never pressured into it, but it's like the dieter who's offered some chocolate cake — it's there, it looks sooo good, and the fact that other people are doing it makes it seem more "okay.") Thanks so much.

What are the effects of sniffing lighter fluid? I recently had a friend sit in a car to listen to music and smell lighter fluid. He tells me he gets a high from this. What are the effects of doing this? I would appreciate this to educate my friend.

I have two friends who were recently diagnosed with depression. They were both prescribed Prozac by their respective doctors. Both of them are heavy marijuana users and both failed to mention that to their doctors. One has been on Prozac for two months and the other for six weeks. I have noticed that their behavior has become strange: mood swings, paranoia, oversleeping, fatigue. They continue taking their Prozac (20 mg a day) and continue smoking pot. I am afraid that there might be some negative interaction between the substances, one being an antidepressant and the other a depressant. Can you provide some insight?

I have been reading some studies that state a correlation between the "religious experience" generated by the psilocybin in magic mushrooms and LSD, and an alleviation of body dysmorphic, obsessive compulsive, and other related disorders. I was wondering if this is anything being pursued, whether these effects have been proven, and how long the symptoms are alleviated for if this is the case. Are there any specific conditions that must be met in order to avoid a "bad trip"? I know people experiencing any kind of mood disorder are succeptable as such.

1) I am wondering about the direct effects nitrous oxide has on the brain, and if it is a fallacy that it kills brain cells.

2) What are the health dangers of inhaling nitrous oxide? I have heard people say that it "kills brain cells," but no one seems to know how, to what extent, and what the resulting effects are. Since nitrous oxide is commonly administered as anesthesia, is there a safe way to consume it for recreational use? If the user controls her oxygen intake, do the harmful effects (if any) still occur?

I have a friend at school who quit smoking last year in January, and went back to it in October. I have no idea why, and he also started doing other drugs, such as smoking blunts, doing ecstasy, and taking steroids. The drug that I am worried about him doing the most is ecstasy, because it's a dangerous drug. Also, he is always talking about doing drugs. How can I help him? I still want him to be my friend. Please help. This is serious.

Lately, I have been doing a drug called Special K. I know it is a sedative/tranquilizer (what's the difference?), but very little about side effects, etc. Also, can you go over similar information about the drug X?

I have a huge dilemma. I have an addiction to a certain drug that has turned my life upside down. That drug is crack cocaine. The worst part about it is that nobody knows this but me. Nobody knows that right now, my life is on the brink. How do you express this problem to people who don't even have a clue as to what you are dealing with? How do you reach out to the people who you love and trust when you are so ashamed of the truth? One thing that I do know is that I'd better do something fast because if I don't, I will lose my fight with life. HELP!!

I have been trying to find information about the hope for recovery for previous meth users, but there doesn't seem to be a consensus. Some sources say that meth causes permanent damage to the brain, while others are a little more hopeful and say some important brain functions might recover.

I used meth about fifteen times, which I gather isn't a lot in comparison to other meth users but is still a considerable amount. For a while I have felt paranoid and anxious and it has been more difficult to perform daily tasks and just generally think straight. Also, things I used to enjoy are not really that enjoyable anymore.

My question is, will I be able to have my brain back? If so, how much of it? Will I ever go back to being my old self?

I have become interested in trying LSD. But I am worried about what the side effects are and the consequences later in life. I only want to try and have no real need to continue, or desire to, for that matter. I am just really curious. What could happen to me? And do you know where one might find such drugs?