Is there a connection between cortisol, depression, and weight loss?

I recently went to my doctor because I've been unable to lose weight. I've been on a successful diet, accompanied with a reasonable exercise plan, but I've seen no real results. A series of tests were run — I've got optimum blood pressure, low cholesterol, and I am not diabetic. But, when my cortisol levels were checked — they were very high. The doctor suspected there was a possibility that I might have Cushings' Syndrome — but another test was run and that came up negative.

I was doing research on the internet, and I found that there was a link between excessive cortisol and depression. I was diagnosed with clinical depression when I was 12 (I am now 21). And I am currently untreated. What is the link between cortisol levels and depression? Are excessive cortisol levels a physical manifestation of depression? Or does an excess of cortisol for some other reason cause depression? Does an excessive amount of cortisol cause weight gain, or in my case prohibit weight loss? And if there is a connection — will treatment for my clinical depression (in the form of prescription pills) help me?

I've been unable to find answers anywhere, or at least a good source to tell me to stop worrying — any help would be appreciated.


Is it possible to reopen a closed piercing?

I have two piercings in each earlobe; however I have not worn earrings in the second set of holes for several years. Recently I tried to insert earrings into the seldom-used pierce holes. One earring went in with no problem, but the second did not go through after several attempts (I actually gave up because my last attempt bent the earring post). I have tried inserting other earrings but they also will not go all the way through. Is this something I can fix myself? Do I have to get the same hole professionally re-pierced? Will there be problems with scar tissue at the site?


Why are my wounds healing more slowly?

I have noticed lately that wounds such as cuts are healing much more slowly than before. I have also noticed that I am scarring more. For example, a tiny hole in my hand has developed a scar that is four times the size of the actual injury, and it is slightly raised. Am I missing something in my diet that is causing this? Or could it be an effect from on-going stress and anxiety? I am a vegetarian with some vegan tendencies, and I take a multi-vitamin every day or so.


Is the bump on the side of my anus hemorrhoids or something else?

1) This is sort of an embarrassing question...Recently I found out that there is something unusual just outside of my anus. It has grown like a pea. When I touch it, it is sort of hard but smooth, and it hurts a bit. What should I do? Is this like some kind of cancer?

2) I have this problem and I am too embarrassed to ask a doctor about it. I am a nineteen-year-old male and have this growth in my anus. It popped up about one week ago. It is about the size of a pea. Could it be hemorrhoids? If not, what can it be? Should I be worried, and what should I do about it?