Since orgasms cause a release of endorphins into one's cerebral-spinal fluid and endorphins are also somewhat responsible for the emotion of happiness, etc., is it possible that excessive masturbation and/or intercourse would lead to a depleted level of endorphins in the system that could in turn cause one's affect to become somewhat "flat"? Could a sustained low level of endorphins in the system induce depression and/or mood disorder?

Hi! I have a question about orgasms. I'm a female who has masturbated since her early teens and wonder if I've "overdone" it somewhat. I did it so frequently (sometimes every other day or so; sometimes I waited longer) that now that I'm in my early 20s, I find it harder to reach orgasm, and harder to have multiple orgasms (it used to come so easily to me). Have I "lost" that momentum? Can I regain it if, say, I stopped masturbating for several weeks or months?

Also, my partner stimulates me manually or with his tongue, and I haven't been able to "come" yet... is it because I've masturbated too much? Do women take longer to come? I think he gets bored doing it...

I have recently been advised that my on-going migraines might be caused and/or increased by the use of contraceptives containing estrogen. To that end, I have been recommended to switch to a progesterone-only form of birth control. Which, in turn, basically means I get to choose between Implanon and Mirena (I really can't stand needles, so Depo is out for me!). I am only 23 years old, and have not yet started a family. I do want to have children someday, and am very enticed by the idea of Mirena lasting to the point when I might want to begin trying to get pregnant. However, all of the advertisements for Mirena state that ideal candidates have already had children.

Is Mirena still safe for use in women who have not yet given birth? If so are there any additional side effects to consider in this instance?

I am not sure who the father of my son is. Is it possible to tell the father of the baby simply by knowing blood types and Rh factors of myself and the potential fathers?

My wife and I had our first child last July. Until about 3 months ago, she was unable to reach orgasm at all. Of late, she has very small one's, but they don't seem to be getting much better. Prior to having the baby, she had strong, very quick (3-5 minutes) orgasms 90% of the time. I know the stress of being at work rather than home with the baby could play a part in this. Is this common and is there a way to mitigate the problem? 

If one has a long-term partner and neither AIDS nor any other STD is a concern, is there any medical reason not to perform cunnilingus on a menstruating woman? My significant other is particularly horny during her period and would love cunnilingus at this time. I am willing but curious.

I'm a 19-year-old female. I had my right ovary removed (oophorectomy) three years ago due to a very large ovarian cyst. I was assured by my gynecologist that I'm still capable of bearing children but wasn't informed thoroughly of all of the pros and cons in regards to this type of operation (e.g., can the estrogen loss have any negative physical affects?). If you could shed some light on this matter, it would be greatly appreciated. Thanks.